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Regulation of Tumor Immune Surveillance and Tumor Immune Subversion by TGF-β
Transforming growth factor-β (TGF-β) is a highly pleiotropic cytokine playing pivotal roles in immune regulation. TGF-β facilitates tumor cell survival and metastasis by targeting multiple cellular components. Focusing on its immunosuppressive functions, TGF-β antagonists have been employed for canc...
Autores principales: | Park, Hae-Young, Wakefield, Lalage M, Mamura, Mizuko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816944/ https://www.ncbi.nlm.nih.gov/pubmed/20157598 http://dx.doi.org/10.4110/in.2009.9.4.122 |
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