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Tiul1 and TGIF are Involved in Downregulation of TGFβ1-induced IgA Isotype Expression
TGF-β1 is well known to induce Ig germ-line α (GLα) transcription and subsequent IgA isotype class switching recombination (CSR). Homeodomain protein TG-interacting factor (TGIF) and E3-ubiquitin ligases TGIF interacting ubiquitin ligase 1 (Tiul1) are implicated in the negative regulation of TGF-β s...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816958/ https://www.ncbi.nlm.nih.gov/pubmed/20157612 http://dx.doi.org/10.4110/in.2009.9.6.248 |