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Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

PTEN is a tumour suppressor with phosphatase activity in vitro against both lipids and proteins and other potential non-enzymatic mechanisms of action. Although the importance of PTEN’s lipid phosphatase activity in regulating the PI3K signalling pathway is recognised, the significance of PTEN’s oth...

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Detalles Bibliográficos
Autores principales: Davidson, Lindsay, Maccario, Helene, Perera, Nevin M., Yang, Xuesong, Spinelli, Laura, Tibarewal, Priyanka, Glancy, Ben, Gray, Alex, Weijer, Cornelis J., Downes, C. Peter, Leslie, Nick R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816976/
https://www.ncbi.nlm.nih.gov/pubmed/19915616
http://dx.doi.org/10.1038/onc.2009.384