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Extracellular BCL2 Proteins Are Danger-Associated Molecular Patterns That Reduce Tissue Damage in Murine Models of Ischemia-Reperfusion Injury

BACKGROUND: Ischemia-reperfusion (I/R) injury contributes to organ dysfunction in a variety of clinical disorders, including myocardial infarction, stroke, organ transplantation, and hemorrhagic shock. Recent investigations have demonstrated that apoptosis as an important mechanism of cell death lea...

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Detalles Bibliográficos
Autores principales: Iwata, Akiko, Morgan-Stevenson, Vicki, Schwartz, Barbara, Liu, Li, Tupper, Joan, Zhu, Xiaodong, Harlan, John, Winn, Robert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816997/
https://www.ncbi.nlm.nih.gov/pubmed/20161703
http://dx.doi.org/10.1371/journal.pone.0009103