Estimates of Positive Darwinian Selection Are Inflated by Errors in Sequencing, Annotation, and Alignment

Published estimates of the proportion of positively selected genes (PSGs) in human vary over three orders of magnitude. In mammals, estimates of the proportion of PSGs cover an even wider range of values. We used 2,980 orthologous protein-coding genes from human, chimpanzee, macaque, dog, cow, rat,...

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Detalles Bibliográficos
Autores principales: Schneider, Adrian, Souvorov, Alexander, Sabath, Niv, Landan, Giddy, Gonnet, Gaston H., Graur, Dan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817407/
https://www.ncbi.nlm.nih.gov/pubmed/20333182
http://dx.doi.org/10.1093/gbe/evp012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817407/
https://www.ncbi.nlm.nih.gov/pubmed/20333182
http://dx.doi.org/10.1093/gbe/evp012

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