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Estimates of Positive Darwinian Selection Are Inflated by Errors in Sequencing, Annotation, and Alignment
Published estimates of the proportion of positively selected genes (PSGs) in human vary over three orders of magnitude. In mammals, estimates of the proportion of PSGs cover an even wider range of values. We used 2,980 orthologous protein-coding genes from human, chimpanzee, macaque, dog, cow, rat,...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817407/ https://www.ncbi.nlm.nih.gov/pubmed/20333182 http://dx.doi.org/10.1093/gbe/evp012 |