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Similarly Strong Purifying Selection Acts on Human Disease Genes of All Evolutionary Ages

A number of studies have showed that recently created genes differ from the genes created in deep evolutionary past in many aspects. Here, we determined the age of emergence and propensity for gene loss (PGL) of all human protein–coding genes and compared disease genes with non-disease genes in term...

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Detalles Bibliográficos
Autores principales: Cai, James J., Borenstein, Elhanan, Chen, Rong, Petrov, Dmitri A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817408/
https://www.ncbi.nlm.nih.gov/pubmed/20333184
http://dx.doi.org/10.1093/gbe/evp013