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Similarly Strong Purifying Selection Acts on Human Disease Genes of All Evolutionary Ages
A number of studies have showed that recently created genes differ from the genes created in deep evolutionary past in many aspects. Here, we determined the age of emergence and propensity for gene loss (PGL) of all human protein–coding genes and compared disease genes with non-disease genes in term...
Autores principales: | Cai, James J., Borenstein, Elhanan, Chen, Rong, Petrov, Dmitri A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817408/ https://www.ncbi.nlm.nih.gov/pubmed/20333184 http://dx.doi.org/10.1093/gbe/evp013 |
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