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High-Resolution Mapping of Evolutionary Trajectories in a Phage
Experimental evolution in rapidly reproducing viruses offers a robust means to infer substitution trajectories during evolution. But with conventional approaches, this inference is limited by how many individual genotypes can be sampled from the population at a time. Low-frequency changes are diffic...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817424/ https://www.ncbi.nlm.nih.gov/pubmed/20333199 http://dx.doi.org/10.1093/gbe/evp029 |