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A single-molecule assay for telomerase structure-function analysis

The activity of the telomerase ribonucleoprotein enzyme is essential for the maintenance of genome stability and normal cell development. Despite the biomedical importance of telomerase activity, detailed structural models for the enzyme remain to be established. Here we report a single-molecule ass...

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Detalles Bibliográficos
Autores principales: Wu, John Y., Stone, Michael D., Zhuang, Xiaowei
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817460/
https://www.ncbi.nlm.nih.gov/pubmed/19920121
http://dx.doi.org/10.1093/nar/gkp1033