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A single-molecule assay for telomerase structure-function analysis
The activity of the telomerase ribonucleoprotein enzyme is essential for the maintenance of genome stability and normal cell development. Despite the biomedical importance of telomerase activity, detailed structural models for the enzyme remain to be established. Here we report a single-molecule ass...
Autores principales: | Wu, John Y., Stone, Michael D., Zhuang, Xiaowei |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817460/ https://www.ncbi.nlm.nih.gov/pubmed/19920121 http://dx.doi.org/10.1093/nar/gkp1033 |
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