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Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions
Cells respond to environmental stress by inducing translation of a subset of mRNAs important for survival or apoptosis. CHOP, a downstream transcriptional target of stress-induced ATF4, is also regulated translationally in a uORF-dependent manner under stress. Low concentration of anisomycin induces...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817461/ https://www.ncbi.nlm.nih.gov/pubmed/19934253 http://dx.doi.org/10.1093/nar/gkp1034 |