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Dna2 is a structure-specific nuclease, with affinity for 5′-flap intermediates

Dna2 is a nuclease/helicase with proposed roles in DNA replication, double-strand break repair and telomere maintenance. For each role Dna2 is proposed to process DNA substrates with a 5′-flap. To date, however, Dna2 has not revealed a preference for binding or cleavage of flaps over single-stranded...

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Detalles Bibliográficos
Autores principales: Stewart, Jason A., Campbell, Judith L., Bambara, Robert A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817469/
https://www.ncbi.nlm.nih.gov/pubmed/19934252
http://dx.doi.org/10.1093/nar/gkp1055