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The helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway

Xeroderma pigmentosum factor D (XPD) is a 5′–3′ superfamily 2 helicase and the founding member of a family of DNA helicases with iron–sulphur cluster domains. As a component of transcription factor II H (TFIIH), XPD is involved in DNA unwinding during nucleotide excision repair (NER). Archaeal XPD i...

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Detalles Bibliográficos
Autores principales: Rudolf, Jana, Rouillon, Christophe, Schwarz-Linek, Ulrich, White, Malcolm F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817471/
https://www.ncbi.nlm.nih.gov/pubmed/19933257
http://dx.doi.org/10.1093/nar/gkp1058