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Algorithmic Assessment of Vaccine-Induced Selective Pressure and Its Implications on Future Vaccine Candidates

Posttrial assessment of a vaccine's selective pressure on infecting strains may be realized through a bioinformatic tool such as parsimony phylogenetic analysis. Following a failed gonococcal pilus vaccine trial of Neisseria gonorrhoeae, we conducted a phylogenetic analysis of pilin DNA and pre...

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Detalles Bibliográficos
Autores principales: Abu-Asab, Mones S., Laassri, Majid, Amri, Hakima
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817498/
https://www.ncbi.nlm.nih.gov/pubmed/20150957
http://dx.doi.org/10.1155/2010/178069