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Improved methods for magnetic purification of malaria parasites and haemozoin

BACKGROUND: Malaria parasites generate free haem upon catabolism of host haemoglobin during their intraerythrocytic growth cycle. In order to minimize oxidative toxicity of the ferric iron, the free haem molecules are polymerized into the biomineral beta-haematin (commonly referred to as haemozoin)....

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Detalles Bibliográficos
Autores principales: Kim, Charles C, Wilson, Emily B, DeRisi, Joseph L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817699/
https://www.ncbi.nlm.nih.gov/pubmed/20074366
http://dx.doi.org/10.1186/1475-2875-9-17