Telomere Shortening Sensitizes Cancer Cells to Selected Cytotoxic Agents: In Vitro and In Vivo Studies and Putative Mechanisms

BACKGROUND: Telomere/telomerase system has been recently recognized as an attractive target for anticancer therapy. Telomerase inhibition results in tumor regression and increased sensitivity to various cytotoxic drugs. However, it has not been fully established yet whether the mediator of these eff...

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Detalles Bibliográficos
Autores principales: Uziel, Orit, Beery, Einat, Dronichev, Vladimir, Samocha, Katty, Gryaznov, Sergei, Weiss, Lola, Slavin, Shimon, Kushnir, Michal, Nordenberg, Yardena, Rabinowitz, Claudette, Rinkevich, Baruch, Zehavi, Tania, Lahav, Meir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817744/
https://www.ncbi.nlm.nih.gov/pubmed/20161752
http://dx.doi.org/10.1371/journal.pone.0009132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817744/
https://www.ncbi.nlm.nih.gov/pubmed/20161752
http://dx.doi.org/10.1371/journal.pone.0009132

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