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The Roles of Streptozotocin Neurotoxicity and Neutral Endopeptidase in Murine Experimental Diabetic Neuropathy

We demonstrated that inhibition of neutral endopeptidase (NEP), a protease that degrades vaso- and neuroactive peptides, improves vascular and neural function in diabetic animal models. In this study we explored the role of NEP in neuropathy related to either insulin-deficient diabetes or diet-induc...

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Detalles Bibliográficos
Autores principales: Davidson, Eric, Coppey, Lawrence, Lu, Bao, Arballo, Victor, Calcutt, Nigel A., Gerard, Craig, Yorek, Mark
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817866/
https://www.ncbi.nlm.nih.gov/pubmed/20148083
http://dx.doi.org/10.1155/2009/431980