Evidence for the Involvement of DNA Repair Enzyme NEIL1 in Nucleotide Excision Repair of (5′R)- and (5′S)-8,5′-Cyclo-2′-deoxyadenosines

[Image: see text] The DNA repair enzyme NEIL1 is a DNA glycosylase that is involved in the first step of base excision repair (BER) of oxidatively induced DNA damage. NEIL1 exhibits a strong preference for excision of 4,6-diamino-5-formamidopyrimidine (FapyAde) and 2,6-diamino-4-hydroxy-5-formamidop...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaruga, Pawel, Xiao, Yan, Vartanian, Vladimir, Lloyd, R. Stephen, Dizdaroglu, Miral
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817919/
https://www.ncbi.nlm.nih.gov/pubmed/20067321
http://dx.doi.org/10.1021/bi902161f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817919/
https://www.ncbi.nlm.nih.gov/pubmed/20067321
http://dx.doi.org/10.1021/bi902161f

Ejemplares similares