Potent anti-tumor effects of a dual specific oncolytic adenovirus expressing apoptin in vitro and in vivo

BACKGROUND: Oncolytic virotherapy is an attractive drug platform of cancer gene therapy, but efficacy and specificity are important prerequisites for success of such strategies. Previous studies determined that Apoptin is a p53 independent, bcl-2 insensitive apoptotic protein with the ability to spe...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Li, Yan, Liu, Zhongmei, Wen, Chang, Li, Huijun, Lu, Mingyao, Tian, Kuoshi, Jin, Lili, Sun, Pegn, Gao, Encheng, Yang, Xiaohong, Xu, Shifu, Kan, Zhuoyue, Wang, Yuhang, Wang, Ningyi, Jin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818692/
https://www.ncbi.nlm.nih.gov/pubmed/20085660
http://dx.doi.org/10.1186/1476-4598-9-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818692/
https://www.ncbi.nlm.nih.gov/pubmed/20085660
http://dx.doi.org/10.1186/1476-4598-9-10

Ejemplares similares