MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells

BACKGROUND: Cancer cells utilize a variety of mechanisms to evade immune detection and attack. Effective immune detection largely relies on the formation of an immune synapse which requires close contact between immune cells and their targets. Here, we show that MUC16, a heavily glycosylated 3-5 mil...

Descripción completa

Detalles Bibliográficos
Autores principales: Gubbels, Jennifer AA, Felder, Mildred, Horibata, Sachi, Belisle, Jennifer A, Kapur, Arvinder, Holden, Helen, Petrie, Sarah, Migneault, Martine, Rancourt, Claudine, Connor, Joseph P, Patankar, Manish S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818693/
https://www.ncbi.nlm.nih.gov/pubmed/20089172
http://dx.doi.org/10.1186/1476-4598-9-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818693/
https://www.ncbi.nlm.nih.gov/pubmed/20089172
http://dx.doi.org/10.1186/1476-4598-9-11

Ejemplares similares