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Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice

BACKGROUND: The aim of this study is to examine the safety and distribution of Ad-EGFP-MDR1, an adenovirus encoding human multidurg resistance gene (human MDR1), in the mice colon carcinoma model. METHODS: After bone marrow cells (BMCs) were infected with Ad-EGFP-MDR1, they were administered by intr...

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Detalles Bibliográficos
Autores principales: Zhao, ZhenZhen, Liu, Wei, Su, YuXi, Zhu, Jin, Zheng, GaiHuan, Luo, Qing, Jin, XianQing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819043/
https://www.ncbi.nlm.nih.gov/pubmed/20044941
http://dx.doi.org/10.1186/1756-9966-29-1