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Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE(2 )in primary rat microglia

BACKGROUND: Recent studies suggest an important role for neurotransmitters as modulators of inflammation. Neuroinflammatory mediators such as cytokines and molecules of the arachidonic acid pathway are generated and released by microglia. The monoamine norepinephrine reduces the production of cytoki...

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Detalles Bibliográficos
Autores principales: Schlachetzki, Johannes CM, Fiebich, Bernd L, Haake, Elisabeth, de Oliveira, Antonio CP, Candelario-Jalil, Eduardo, Heneka, Michael T, Hüll, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819253/
https://www.ncbi.nlm.nih.gov/pubmed/20064241
http://dx.doi.org/10.1186/1742-2094-7-2