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Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE(2 )in primary rat microglia
BACKGROUND: Recent studies suggest an important role for neurotransmitters as modulators of inflammation. Neuroinflammatory mediators such as cytokines and molecules of the arachidonic acid pathway are generated and released by microglia. The monoamine norepinephrine reduces the production of cytoki...
Autores principales: | Schlachetzki, Johannes CM, Fiebich, Bernd L, Haake, Elisabeth, de Oliveira, Antonio CP, Candelario-Jalil, Eduardo, Heneka, Michael T, Hüll, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819253/ https://www.ncbi.nlm.nih.gov/pubmed/20064241 http://dx.doi.org/10.1186/1742-2094-7-2 |
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