Dual action of epidermal growth factor: extracellular signal-stimulated nuclear–cytoplasmic export and coordinated translation of selected messenger RNA

We report the first example of a coordinated dual action of epidermal growth factor (EGF) in stimulating the nuclear–cytoplasmic export and translation of a select messenger RNA (mRNA). The effect of EGF is mediated by the RNA-binding protein Grb7 (growth factor receptor–bound protein 7), which serv...

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Detalles Bibliográficos
Autores principales: Tsai, Nien-Pei, Lin, Ya-Lun, Tsui, Yao-Chen, Wei, Li-Na
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819679/
https://www.ncbi.nlm.nih.gov/pubmed/20142421
http://dx.doi.org/10.1083/jcb.200910083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819679/
https://www.ncbi.nlm.nih.gov/pubmed/20142421
http://dx.doi.org/10.1083/jcb.200910083

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