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Dual action of epidermal growth factor: extracellular signal-stimulated nuclear–cytoplasmic export and coordinated translation of selected messenger RNA
We report the first example of a coordinated dual action of epidermal growth factor (EGF) in stimulating the nuclear–cytoplasmic export and translation of a select messenger RNA (mRNA). The effect of EGF is mediated by the RNA-binding protein Grb7 (growth factor receptor–bound protein 7), which serv...
Autores principales: | Tsai, Nien-Pei, Lin, Ya-Lun, Tsui, Yao-Chen, Wei, Li-Na |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819679/ https://www.ncbi.nlm.nih.gov/pubmed/20142421 http://dx.doi.org/10.1083/jcb.200910083 |
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