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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
Most solid tumors are aneuploid, and it has been proposed that aneuploidy is the consequence of an elevated rate of chromosome missegregation in a process called chromosomal instability (CIN). However, the relationship of aneuploidy and CIN is unclear because the proliferation of cultured diploid ce...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819684/ https://www.ncbi.nlm.nih.gov/pubmed/20123995 http://dx.doi.org/10.1083/jcb.200905057 |