Cargando…

Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis

Rapid neurotransmitter release depends on the ability to arrest the SNAP receptor (SNARE)–dependent exocytosis pathway at an intermediate “cocked” state, from which fusion can be triggered by Ca(2+). It is not clear whether this state includes assembly of synaptobrevin (the vesicle membrane SNARE) t...

Descripción completa

Detalles Bibliográficos
Autores principales: Walter, Alexander M., Wiederhold, Katrin, Bruns, Dieter, Fasshauer, Dirk, Sørensen, Jakob B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819690/
https://www.ncbi.nlm.nih.gov/pubmed/20142423
http://dx.doi.org/10.1083/jcb.200907018