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Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3

Epithelial–myofibroblast (MF) transition (EMyT) is a critical process in organ fibrosis, leading to α–smooth muscle actin (SMA) expression in the epithelium. The mechanism underlying the activation of this myogenic program is unknown. We have shown previously that both injury to intercellular contac...

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Detalles Bibliográficos
Autores principales: Masszi, András, Speight, Pam, Charbonney, Emmanuel, Lodyga, Monika, Nakano, Hiroyasu, Szászi, Katalin, Kapus, András
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819691/
https://www.ncbi.nlm.nih.gov/pubmed/20123992
http://dx.doi.org/10.1083/jcb.200906155