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Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3
Epithelial–myofibroblast (MF) transition (EMyT) is a critical process in organ fibrosis, leading to α–smooth muscle actin (SMA) expression in the epithelium. The mechanism underlying the activation of this myogenic program is unknown. We have shown previously that both injury to intercellular contac...
Autores principales: | Masszi, András, Speight, Pam, Charbonney, Emmanuel, Lodyga, Monika, Nakano, Hiroyasu, Szászi, Katalin, Kapus, András |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819691/ https://www.ncbi.nlm.nih.gov/pubmed/20123992 http://dx.doi.org/10.1083/jcb.200906155 |
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