Residual γH2AX foci as an indication of lethal DNA lesions

BACKGROUND: Evidence suggests that tumor cells exposed to some DNA damaging agents are more likely to die if they retain microscopically visible γH2AX foci that are known to mark sites of double-strand breaks. This appears to be true even after exposure to the alkylating agent MNNG that does not cau...

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Detalles Bibliográficos
Autores principales: Banáth, Judit P, Klokov, Dmitry, MacPhail, Susan H, Banuelos, C Adriana, Olive, Peggy L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819996/
https://www.ncbi.nlm.nih.gov/pubmed/20051134
http://dx.doi.org/10.1186/1471-2407-10-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819996/
https://www.ncbi.nlm.nih.gov/pubmed/20051134
http://dx.doi.org/10.1186/1471-2407-10-4

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