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Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth

BACKGROUND: Apoptosis caused by inadequate or inappropriate cell-matrix interactions is defined as anoikis. Although transformed cells are known to be anoikis-resistant, the underlying mechanisms have not been well understood. We investigated the mechanisms of anoikis resistance of tumor cells. RESU...

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Detalles Bibliográficos
Autores principales: Zhang, Xing, Xu, Li-hua, Yu, Qiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820017/
https://www.ncbi.nlm.nih.gov/pubmed/20074345
http://dx.doi.org/10.1186/1476-4598-9-7