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Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells

BACKGROUND: Myeloid cell leukemia-1 (Mcl-1) is a member of the Bcl-2 family, which inhibits cell apoptosis by sequestering pro-apoptotic proteins Bim and Bid. Mcl-1 overexpression has been associated with progression in leukemia and some solid tumors including prostate cancer (PCa). However, the reg...

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Detalles Bibliográficos
Autores principales: Zhang, Shumin, Zhau, Haiyen E, Osunkoya, Adeboye O, Iqbal, Shareen, Yang, Xiaojian, Fan, Songqing, Chen, Zhengjia, Wang, Ruoxiang, Marshall, Fray F, Chung, Leland WK, Wu, Daqing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820018/
https://www.ncbi.nlm.nih.gov/pubmed/20085644
http://dx.doi.org/10.1186/1476-4598-9-9