Monitoring Genomic Sequences during SELEX Using High-Throughput Sequencing: Neutral SELEX

BACKGROUND: SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers. Genomic SELEX transforms SELEX into a tool to discover novel, genomically encoded RNA or DNA sequences binding a ligand of interest, called genomic aptam...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimmermann, Bob, Gesell, Tanja, Chen, Doris, Lorenz, Christina, Schroeder, Renée
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820082/
https://www.ncbi.nlm.nih.gov/pubmed/20161784
http://dx.doi.org/10.1371/journal.pone.0009169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820082/
https://www.ncbi.nlm.nih.gov/pubmed/20161784
http://dx.doi.org/10.1371/journal.pone.0009169

Ejemplares similares