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Monitoring Genomic Sequences during SELEX Using High-Throughput Sequencing: Neutral SELEX
BACKGROUND: SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers. Genomic SELEX transforms SELEX into a tool to discover novel, genomically encoded RNA or DNA sequences binding a ligand of interest, called genomic aptam...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820082/ https://www.ncbi.nlm.nih.gov/pubmed/20161784 http://dx.doi.org/10.1371/journal.pone.0009169 |