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Cytotoxic Aggregation and Amyloid Formation by the Myostatin Precursor Protein

Myostatin, a negative regulator of muscle growth, has been implicated in sporadic inclusion body myositis (sIBM). sIBM is the most common age-related muscle-wastage disease with a pathogenesis similar to that of amyloid disorders such as Alzheimer's and Parkinson's diseases. Myostatin prec...

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Detalles Bibliográficos
Autores principales: Starck, Carlene S., Sutherland-Smith, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820090/
https://www.ncbi.nlm.nih.gov/pubmed/20161792
http://dx.doi.org/10.1371/journal.pone.0009170