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CXCR7 Functions as a Scavenger for CXCL12 and CXCL11

BACKGROUND: CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine receptors, but fails to couple to G-proteins and to induce typical chemokine receptor mediated cellular responses. The function of CXCR7 is controversial. Some studies sugge...

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Detalles Bibliográficos
Autores principales: Naumann, Ulrike, Cameroni, Elisabetta, Pruenster, Monika, Mahabaleshwar, Harsha, Raz, Erez, Zerwes, Hans-Günter, Rot, Antal, Thelen, Marcus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820091/
https://www.ncbi.nlm.nih.gov/pubmed/20161793
http://dx.doi.org/10.1371/journal.pone.0009175