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Complement Component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort

PURPOSE: A non-synonymous single nucleotide polymorphism (SNP) in complement component 3 has been shown to increase the risk of age-related macular degeneration (AMD). We assess its effect on AMD risk in a Northern Irish sample, test for gene–gene and gene–environment interaction, and review a risk...

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Detalles Bibliográficos
Autores principales: McKay, Gareth J., Dasari, Shilpa, Patterson, Christopher C., Chakravarthy, Usha, Silvestri, Giuliana
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820106/
https://www.ncbi.nlm.nih.gov/pubmed/20157618