Quantitative Expression of TMPRSS2 Transcript in Prostate Tumor Cells Reflects TMPRSS2-ERG Fusion Status

TMPRSS2-ERG fusion is the most common oncogenic rearrangement in prostate cancer (CaP). Due to this chromosomal rearrangement one TMPRSS2 allele loses its promoter, and one of the ERG alleles gains that promoter leading to its overexpression in these tumor cells. Some studies suggest that TMPRSS2, a...

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Detalles Bibliográficos
Autores principales: Mwamukonda, Kuwong, Chen, Yongmei, Ravindranath, Lakshmi, Furusato, Bungo, Hu, Ying, Sterbis, Joseph, Osborn, David, Rosner, Inger, Sesterhenn, Isabell A., McLeod, David G., Srivastava, Shiv, Petrovics, Gyorgy
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820150/
https://www.ncbi.nlm.nih.gov/pubmed/19597533
http://dx.doi.org/10.1038/pcan.2009.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820150/
https://www.ncbi.nlm.nih.gov/pubmed/19597533
http://dx.doi.org/10.1038/pcan.2009.28

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