Cargando…

Rottlerin Inhibits ROS Formation and Prevents NFκB Activation in MCF-7 and HT-29 Cells

Rottlerin, a polyphenol isolated from Mallotus Philippinensis, has been recently used as a selective inhibitor of PKC δ, although it can inhibit many kinases and has several biological effects. Among them, we recently found that Rottlerin inhibits the Nuclear Factor κB (NFκB), activated by either ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Maioli, Emanuela, Greci, Lucedio, Soucek, Karel, Hyzdalova, Martina, Pecorelli, Alessandra, Fortino, Vittoria, Valacchi, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820285/
https://www.ncbi.nlm.nih.gov/pubmed/20168983
http://dx.doi.org/10.1155/2009/742936