Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification

Immunity to one of the four dengue virus (DV) serotypes can increase disease severity in humans upon subsequent infection with another DV serotype. Serotype cross-reactive antibodies facilitate DV infection of myeloid cells in vitro by promoting virus entry via Fcγ receptors (FcγR), a process known...

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Detalles Bibliográficos
Autores principales: Balsitis, Scott J., Williams, Katherine L., Lachica, Ruben, Flores, Diana, Kyle, Jennifer L., Mehlhop, Erin, Johnson, Syd, Diamond, Michael S., Beatty, P. Robert, Harris, Eva
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820409/
https://www.ncbi.nlm.nih.gov/pubmed/20168989
http://dx.doi.org/10.1371/journal.ppat.1000790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820409/
https://www.ncbi.nlm.nih.gov/pubmed/20168989
http://dx.doi.org/10.1371/journal.ppat.1000790

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