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Apyrase treatment of myocardial infarction according to a clinically applicable protocol fails to reduce myocardial injury in a porcine model

BACKGROUND: Ectonucleotidase dependent adenosine generation has been implicated in preconditioning related cardioprotection against ischemia-reperfusion injury, and treatment with a soluble ectonucleotidase has been shown to reduce myocardial infarct size (IS) when applied prior to induction of isch...

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Detalles Bibliográficos
Autores principales: van der Pals, Jesper, Koul, Sasha, Götberg, Michael I, Olivecrona, Göran K, Ugander, Martin, Kanski, Mikael, Otto, Andreas, Götberg, Matthias, Arheden, Håkan, Erlinge, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820435/
https://www.ncbi.nlm.nih.gov/pubmed/20047685
http://dx.doi.org/10.1186/1471-2261-10-1