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Temporal changes in incidence and pattern of central nervous system relapses in children with acute lymphoblastic leukaemia treated on four consecutive Medical Research Council Trials, 1985–2001

Despite the success of contemporary treatment protocols in childhood acute lymphoblastic leukaemia (ALL), relapse within the central nervous system (CNS) remains a challenge. To better understand this phenomenon, we have analysed the changes in incidence and pattern of CNS relapses in 5564 children...

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Detalles Bibliográficos
Autores principales: Krishnan, Shekhar, Wade, Rachel, Moorman, Anthony V, Mitchell, Chris, Kinsey, Sally E, Eden, TOB, Parker, Catriona, Vora, Ajay, Richards, Sue, Saha, Vaskar
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820451/
https://www.ncbi.nlm.nih.gov/pubmed/20016529
http://dx.doi.org/10.1038/leu.2009.264