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Chemosensitization of cancer cells by siRNA using targeted nanogel delivery

BACKGROUND: Chemoresistance is a major obstacle in cancer treatment. Targeted therapies that enhance cancer cell sensitivity to chemotherapeutic agents have the potential to increase drug efficacy while reducing toxic effects on untargeted cells. Targeted cancer therapy by RNA interference (RNAi) is...

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Detalles Bibliográficos
Autores principales: Dickerson, Erin B, Blackburn, William H, Smith, Michael H, Kapa, Laura B, Lyon, L Andrew, McDonald, John F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820460/
https://www.ncbi.nlm.nih.gov/pubmed/20064265
http://dx.doi.org/10.1186/1471-2407-10-10