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Chemosensitization of cancer cells by siRNA using targeted nanogel delivery
BACKGROUND: Chemoresistance is a major obstacle in cancer treatment. Targeted therapies that enhance cancer cell sensitivity to chemotherapeutic agents have the potential to increase drug efficacy while reducing toxic effects on untargeted cells. Targeted cancer therapy by RNA interference (RNAi) is...
Autores principales: | Dickerson, Erin B, Blackburn, William H, Smith, Michael H, Kapa, Laura B, Lyon, L Andrew, McDonald, John F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820460/ https://www.ncbi.nlm.nih.gov/pubmed/20064265 http://dx.doi.org/10.1186/1471-2407-10-10 |
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