Stable alterations of CD44 isoform expression in prostate cancer cells decrease invasion and growth and alter ligand binding and chemosensitivity

BACKGROUND: Dysregulated CD44 expression characterizes most human cancers, including prostate cancer (PCa). PCa loses expression of CD44 standard (CD44s) that is present in benign epithelium, and overexpresses the novel splice variant isoform, CD44v7-10. METHODS: Using retroviral gene delivery to PC...

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Detalles Bibliográficos
Autores principales: Yang, Kui, Tang, Yaqiong, Habermehl, Gabriel K, Iczkowski, Kenneth A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820461/
https://www.ncbi.nlm.nih.gov/pubmed/20074368
http://dx.doi.org/10.1186/1471-2407-10-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820461/
https://www.ncbi.nlm.nih.gov/pubmed/20074368
http://dx.doi.org/10.1186/1471-2407-10-16

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