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Efficient algorithms for analyzing segmental duplications with deletions and inversions in genomes

BACKGROUND: Segmental duplications, or low-copy repeats, are common in mammalian genomes. In the human genome, most segmental duplications are mosaics comprised of multiple duplicated fragments. This complex genomic organization complicates analysis of the evolutionary history of these sequences. On...

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Detalles Bibliográficos
Autores principales: Kahn, Crystal L, Mozes, Shay, Raphael, Benjamin J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820476/
https://www.ncbi.nlm.nih.gov/pubmed/20047668
http://dx.doi.org/10.1186/1748-7188-5-11