Ascorbate inhibition of angiogenesis in aortic rings ex vivo and subcutaneous Matrigel plugs in vivo

BACKGROUND: Angiogenesis is critical to tumor growth and is therefore a potential target for cancer therapy. As many current inhibitors of angiogenesis exhibit host toxicity, natural alternatives are needed. At millimolar concentrations, ascorbate (vitamin C) inhibits migration and tubule formation...

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Detalles Bibliográficos
Autores principales: Mikirova, Nina A, Casciari, Joseph J, Riordan, Neil H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820478/
https://www.ncbi.nlm.nih.gov/pubmed/20150992
http://dx.doi.org/10.1186/2040-2384-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820478/
https://www.ncbi.nlm.nih.gov/pubmed/20150992
http://dx.doi.org/10.1186/2040-2384-2-2

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