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A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity

Corticostriatal synapse plasticity of medium spiny neurons is regulated by glutamate input from the cortex and dopamine input from the substantia nigra. While cortical stimulation alone results in long-term depression (LTD), the combination with dopamine switches LTD to long-term potentiation (LTP),...

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Detalles Bibliográficos
Autores principales: Nakano, Takashi, Doi, Tomokazu, Yoshimoto, Junichiro, Doya, Kenji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820521/
https://www.ncbi.nlm.nih.gov/pubmed/20169176
http://dx.doi.org/10.1371/journal.pcbi.1000670