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A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity
Corticostriatal synapse plasticity of medium spiny neurons is regulated by glutamate input from the cortex and dopamine input from the substantia nigra. While cortical stimulation alone results in long-term depression (LTD), the combination with dopamine switches LTD to long-term potentiation (LTP),...
Autores principales: | Nakano, Takashi, Doi, Tomokazu, Yoshimoto, Junichiro, Doya, Kenji |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820521/ https://www.ncbi.nlm.nih.gov/pubmed/20169176 http://dx.doi.org/10.1371/journal.pcbi.1000670 |
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